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Ahmed Saad Selected Research

Hypoxia (Hypoxemia)

10/2020Renal fibrosis detected by diffusion-weighted magnetic resonance imaging remains unchanged despite treatment in subjects with renovascular disease.
1/2020In a Phase 1a escalating clinical trial, autologous mesenchymal stem cell infusion for renovascular disease increases blood flow and the glomerular filtration rate while reducing inflammatory biomarkers and blood pressure.
1/2019Tissue hypoxia, inflammation, and loss of glomerular filtration rate in human atherosclerotic renovascular disease.
9/2017Phase 2a Clinical Trial of Mitochondrial Protection (Elamipretide) During Stent Revascularization in Patients With Atherosclerotic Renal Artery Stenosis.
11/2016Atherosclerotic renal artery stenosis is associated with elevated cell cycle arrest markers related to reduced renal blood flow and postcontrast hypoxia.
3/2016Differences in GFR and Tissue Oxygenation, and Interactions between Stenotic and Contralateral Kidneys in Unilateral Atherosclerotic Renovascular Disease.
1/2016Urinary Mitochondrial DNA Copy Number Identifies Chronic Renal Injury in Hypertensive Patients.
1/2016Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia.
5/2015Chronic renal ischemia in humans: can cell therapy repair the kidney in occlusive renovascular disease?
3/2015Management of atherosclerotic renovascular disease after Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL).
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Ahmed Saad Research Topics

Disease

11Hypoxia (Hypoxemia)
10/2020 - 08/2013
7Renal Artery Obstruction (Renal Artery Stenosis)
09/2017 - 08/2013
6Solitary Kidney
01/2019 - 08/2013
6Essential Hypertension
03/2016 - 08/2013
5Hypertension (High Blood Pressure)
11/2017 - 04/2010
3Vasculitis (Vasculitides)
12/2021 - 04/2020
3Thrombosis (Thrombus)
12/2021 - 04/2020
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
07/2013 - 11/2012
2Diabetic Retinopathy (Retinopathy, Diabetic)
12/2022 - 02/2019
2Aneurysm (Aneurysms)
12/2021 - 04/2020
2Necrosis
10/2020 - 07/2018
2Atherosclerosis
05/2015 - 03/2015
2Insulin Resistance
07/2013 - 11/2012
1Myopia
02/2024
1Astigmatism
02/2024
1Schizophrenia (Dementia Praecox)
01/2023
1Macular Edema
01/2023
1Lung Neoplasms (Lung Cancer)
11/2022
1Femoral Neck Fractures
07/2022
1Type 2 Diabetes Mellitus (MODY)
03/2022
1Hyperglycemia
03/2022
1Osteoporotic Fractures
03/2022
1Neoplasms (Cancer)
03/2022
1Multifocal Choroiditis
01/2022
1Rupture
12/2021
1Hemoptysis
01/2021
1Pulmonary Embolism
04/2020
1Venous Thrombosis (Deep-Vein Thrombosis)
04/2020
1Diabetes Mellitus
02/2019
1Atrophy
07/2018
1Muscular Atrophy (Muscle Atrophy)
07/2018
1Inflammation (Inflammations)
01/2018
1Infertility (Sterility)
03/2017
1Acute Kidney Injury (Acute Renal Failure)
11/2016
1Edema (Dropsy)
12/2015
1Amyloid Plaque
07/2015
1Amyloidosis
07/2015
1Fibrosis (Cirrhosis)
06/2015
1Ischemia
05/2015
1Renovascular Hypertension (Goldblatt Syndrome)
03/2015

Drug/Important Bio-Agent (IBA)

6Biomarkers (Surrogate Marker)IBA
01/2020 - 08/2013
6CytokinesIBA
01/2020 - 08/2013
4Iothalamic Acid (Iotalamic Acid)FDA Link
01/2019 - 08/2013
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2022 - 01/2016
34- ((1,4,8,11- tetraazacyclotetradec- 1- yl)methyl)benzoic acidIBA
12/2021 - 04/2020
3Lipocalin-2IBA
01/2019 - 08/2013
2Retinaldehyde (Retinal)IBA
01/2023 - 12/2022
2SteroidsIBA
12/2022 - 01/2022
2AntioxidantsIBA
11/2022 - 03/2022
2Caspase 3 (Caspase-3)IBA
11/2022 - 07/2018
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2019 - 08/2013
2erucylphosphocholineIBA
01/2018 - 09/2013
2Mitochondrial DNA (mtDNA)IBA
11/2017 - 01/2016
2MicroRNAs (MicroRNA)IBA
01/2016 - 03/2015
2AngiotensinsIBA
08/2015 - 09/2013
2SodiumIBA
08/2015 - 09/2013
2ReninIBA
08/2015 - 09/2013
2Glucose (Dextrose)FDA LinkGeneric
12/2012 - 11/2012
1Antipsychotic Agents (Antipsychotics)IBA
01/2023
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
11/2022
1AmylasesFDA Link
03/2022
1CarbohydratesIBA
03/2022
1EnzymesIBA
03/2022
1CreatinineIBA
10/2020
1Tumor Biomarkers (Tumor Markers)IBA
10/2020
1Immunologic Factors (Immunomodulators)IBA
04/2020
1Furosemide (Lasix)FDA LinkGeneric
01/2019
1TaurineFDA Link
07/2018
1Contrast MediaIBA
03/2018
1arginyl- 2,'6'- dimethyltyrosyl- lysyl- phenylalaninamideIBA
09/2017
1Clomiphene (Clomifene)FDA LinkGeneric
03/2017
1Nitric Oxide DonorsIBA
03/2017
1insulin-like growth factor binding protein-related protein 1IBA
11/2016
1Tissue Inhibitor of Metalloproteinase-2IBA
11/2016
1Hormones (Hormone)IBA
03/2016
1Fluocinolone Acetonide (Capex)FDA LinkGeneric
12/2015
1Apolipoproteins E (ApoE)IBA
07/2015
1ApolipoproteinsIBA
07/2015
1Immunoglobulin A (IgA)IBA
07/2015
1Amyloid (Amyloid Fibrils)IBA
07/2015
1Immunoglobulins (Immunoglobulin)IBA
07/2015
1Immunoglobulin G (IgG)IBA
07/2015
1Oxygen (Dioxygen)IBA
06/2015
1Thromboplastin (Tissue Factor)IBA
03/2015
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
03/2015
1Plasminogen InactivatorsIBA
03/2015
1lipoprotein-associated coagulation inhibitor (TFPI)IBA
03/2015
1Urokinase Plasminogen Activator ReceptorsIBA
03/2015

Therapy/Procedure

6Therapeutics
12/2022 - 07/2013
5Stents
09/2017 - 08/2013
3Lasers (Laser)
01/2023 - 02/2019
2Artificial Pancreas
07/2013 - 11/2012
1Photorefractive Keratectomy
02/2024
1Keratectomy
02/2024
1Excimer Lasers
02/2024
1Operative Time
07/2022
1Vertebroplasty
03/2022
1Stem Cell Transplantation
07/2015
1Drug Therapy (Chemotherapy)
07/2015
1Cell- and Tissue-Based Therapy (Cell Therapy)
05/2015